Exchange: NASDAQ·Updated 04:00 PM EDT
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PRAX Praxis Precision Medicines Inc

$260.17
$18.41
(7.62%)
Today
EarningsNov 9
Mkt Cap$6.75B
Vol860,776.00

About PRAX

Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company, which engages in the genetic epilepsies into the development of therapies for central nervous system, or CNS, disorders characterized by neuronal excitation-inhibition imbalance. It focuses on two proprietary platforms: Cerebrum and Solidus. The Cerebrum platform utilizes a deep understanding of neuronal excitability and neuronal networks and applies a series of computational and experimental tools to develop orally available precision therapies. The Solidus platform consists of antisense oligonucleotide, or ASO. The company was founded by Kiran Reddy, David Goldstein, and Steven Petrou on September 22, 2015 and is headquartered in Boston, MA.
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Bullish Sentiment

How do you feel about PRAX?

Trainguy1
$PRAX Ulixacaltamide was granted breakthrough therapy designation by the FDA. To get BTD, early clinical trials must demonstrate that the drug offers a major improvement over existing treatments.
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TheContessa
$PRAX Finally pulled the trigger on PRAX and loaded up on this dip. I respect several of the bullish analysts who feel this is a winner. Waiting to buy was not easy, although I bailed on $JAZZ before it dipped. I like both, but went risk-on today with PRAX.
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TheContessa
$PRAX BTIG Research: Raised its price target to $826 from $810 maintaining a Buy rating Oct. 6 ✅ Goldman Sachs: Raised its price target to $575 from $470 with a Buy rating. ✅ Raymond James: Raised its price target to $945 from $765. ✅ JPMorgan & UBS: Initiated coverage with Overweight and Buy ratings respectively in mid-October 2026. ✅ H.C. Wainwright: Reaffirmed a Buy rating with a $1,201 price objective. ✅
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TheContessa
$PRAX This stock is going to deliver longs a treat before Christmas and spectacular profits by Spring of ‘27 or sooner. ✅
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AngusMacbeth
$PRAX i keep adding and it keeps dropping. i’m still feeling very good about this company’s pipeline and i think long term this will be a big, big winner. 🤞🤞🤞
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quassarcapital
$PRAX (Praxis Precision Medicines) gets its price target raised to $534 from $441 by JonesTrading, which maintains a Buy rating, citing progress in the company's late-stage central nervous system drug pipeline.
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brunoq14
$PRAX Now 3 months until Relutrigine PDUFA date, December 27, 2026. Relutrigine holds Priority Review, Breakthrough Therapy, Orphan Drug and Rare Pediatric Disease designations from the FDA.
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heyabbott
$PRAX We wait for fda approval in december and january. Could b e sooner for ulixacaltamide and relutrigene. Vormatrigine is currently paused in late-stage clinical development following mixed results in primary and secondary trial endpoints.
5
Trainguy1
$PRAX As a follow-up to the EMBOLD study, in which PRAX treated SCN2A and SCN8A developmental and epileptic encephalopathy (DEE) patients with Relutrigine, PRAX is currently conducting the broader EMERALD clinical trial. EMERALD is testing Relutrigine across more than 50 distinct genetic etiologies of DEEs. PRAX surpassed their EMERALD enrollment goal of 160 patients, enrolling approximately 200 patients. The topline readout of EMERALD is expected to occur in Q4, 2026. Since clinicaltrials dot gov (NCT07010471) indicates primary completion in DEC 2026, we can expect the read out to occur in December. If the results are good, PRAX plans to submit an sNDA to the FDA for broad DEE approval of Relutrigine.
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Trainguy1
$PRAX Following up with the relutrigine SCN2A- and SCN8A-DEE (developmental and epileptic encephalopathy) EMBOLD trial, Praxis is running their EMERALD trial. EMERALD is a broader trial of relutrigine across more than 50 distinct genetic etiologies of DEEs. PRAX exceeded their initial enrollment target of 160 patients in the EMERALD studt, enrolling approximately 200 patients. Topline results are expected to be read out in the fourth quarter of 2026 and, if positive, could support a supplemental NDA submission in 2027.
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Quantumup
UBS🏁 $PRAX Buy; PT $706 $RAPP $JAZZ SAGE DRUG UCBJY ESAIY OVID XENE UBS said in its initiation report: Praxis has one of the most important biotech catalysts over the next six months, with a January 29, 2027 PDUFA decision for ulixacaltamide in essential tremor—based physician checks, ulixa could see broad adoption across both primary care and specialist settings if approved, but despite this opportunity, shares trade at just 1.5x enterprise value to expected discounted sales vs. a peer median of 3.2x.
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heyabbott
$PRAX The great late Jackie Mason would say…”its supposed to go down...this way you could buy more!!!
3
gerryh57
$PRAX autumn great time here in New England it is time to start lighting the candles and I think i will burn the red ones first. Green balsam is perfect for Christmas. Shopping early is great fun I think should do an add for yankee candles and have fidelity endorse it.
3
miller1m
$PRAX building a sizable position here of 1500 shares plus looking for similar outcome as I experienced with APGE getting eaten up by ABBV rocket 🚀 here much higher!
3
Quantumup
JPMorgan🏁 $PRAX Overweight-$700 and Placed the Ticker on its Positive Catalyst Watch List. $RAPP $JAZZ DRUG SAGE UCBJY ESAIY OVID XENE JPMorgan said in its initiation report -- PRAX has a unique set of assets that could offer benefit in areas of unmet medical need, including ulixacaltamide for essential tremor (ET) and relutrigine for developmental and epileptic encephalopathies (DEEs), which each have PDUFA dates on the horizon in the U.S. as well as supportive data and constructive regulatory commentary to date. Both assets are approvable and have transformative potential in their respective indications.
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Tbitty
$PRAX does anyone know why this keeps dropping? Awfully strange for a company with 2 PDUFAs just a few months away.
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ExitLiquidity69
$PRAX watching this for starting a long term position. Thankful they are researching SCN2A. My daughter has LoF (thankfully) and it is such a rare condition. Wanted to short the 370s, but morally I can only hope for their success for families like mine. Let's goooooo 💪
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HippoCritical
$PRAX going to be reading more into this one.. some top analysts see massive upside here.
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CharlieeMungerTWITS
$PRAX There is meaningful short interest. As of Aug. 31, about 3.74 million shares, or 13.8% of the float, were short, with roughly 10.2 days to cover. That's substantial and can amplify moves in either direction. Relutrigine: PDUFA December 27, 2026 Ulixacaltamide: PDUFA January 29, 2027
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