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WorldFinancial

WorldFinancial ($WLFI) is trending as the community anticipates upcoming news and potential integration with financial services. Bullish sentiment is fueled by discussions of technical patterns like cup and handle formations, as well as speculation around adoption by financial institutions and governments. Community members are actively discussing potential price surges and the broader implications for the altcoin market, with some drawing parallels to other meme coins.

Ethereum is a global, open-source platform for decentralized applications. In other words, the vision is to create a world computer that anyone can build applications in a decentralized manner; while all states and data are distributed and publicly accessible. Ethereum supports smart contracts in which developers can write code in order to program digital value. Examples of decentralized apps (dapps) that are built on Ethereum includes tokens, non-fungible tokens, decentralized finance apps, lending protocol, decentralized exchanges, and much more.  On Ethereum, all transactions and smart contract executions require a small fee to be paid. This fee is called Gas. In technical terms, Gas refers to the unit of measure on the amount of computational effort required to execute an operation or a smart contract. The more complex the execution operation is, the more gas is required to fulfill that operation. Gas fees are paid entirely in Ether (ETH), which is the native coin of the blockchain. The price of gas can fluctuate from time to time depending on the network demand.

Ethereum

Ethereum is trending as the community anticipates potential catalysts such as a US/China trade deal and upcoming rate cuts, while also discussing its potential for a significant price surge. Bullish sentiment is fueled by institutions potentially positioning themselves, as well as anticipation of staking, while some traders point to technical indicators suggesting a breakout. Overall, the community is weighing positive news against ongoing market manipulation concerns.

POET Technologies, Inc. engages in the designing, developing, manufacturing and sale of opto-electronic solutions for the sensing, data communications and telecommunications markets. It developed POET Optical Interposer platform, which allows the integration of electronic and photonic devices into a single multi-chip module. The company was founded on November 14, 1985 and is headquartered in Toronto, Canada.

POET Technologies Inc

POET Technologies is trending due to a recently announced oversubscribed $150 million registered direct offering and a $5 million production order, signaling a shift from R&D to manufacturing. The community is discussing the potential impact of these developments, particularly the Luxshare-Meta connection and the possibility of further purchase orders. Bullish sentiment is fueled by comparisons to previous tech breakouts and the potential for POET's optical interposer technology to revolutionize AI data transmission.

Shibmas was launched on the 9th Of December. The project is a meme token and gives homage to Shiba Inu the token. The token is a playful character who is bringing the Christmas spirit to token holders all around the world. We plan on getting many listings on various exchanges in the coming days. We have over 1000 holders in 24 hours and we aim on getting over 10000 holders within the next week and in the run up to Christmas

Shibmas

Shibmas ($SMAS) is gaining attention, with community members highlighting its potential for a breakout and strong chart setup, particularly within the Phantom Wallet ecosystem. Talk centers around the token's steady performance amid market hesitation and its potential for significant upward momentum. The community emphasizes its growing momentum and accessible entry point.

SSgA Active Trust - SPDR S&P 500 ETF Trust

SPY is trending due to optimism surrounding potential US-China trade deal developments, with discussions covering key trade issues and export controls. Community members are weighing the impact of this framework on the market, especially on futures, with many anticipating a bullish open. Concerns remain about whether this optimism is justified, the details of the deal, and its long-term impact.

Avidity Biosciences, Inc. engages in the development of a new class of oligonucleotide-based therapies called Antibody Oligonucleotide Conjugates (AOC). It utilizes its AOC platform to design, engineer, and develop therapeutics that combine the tissue selectivity of monoclonal antibodies and the precision of oligonucleotide-based therapies in order to access previously undruggable tissue and cell types and more effectively target underlying genetic drivers of diseases. The company was founded by Troy E. Wilson, Kent Hawryluk, Mark E. Davis, and Francis Patrick McCormick on November 13, 2012 and is headquartered in San Diego, CA.

Avidity Biosciences Inc

Avidity Biosciences ($RNA) is trending following Novartis' ($NVS) acquisition agreement, which sent the stock soaring. The community is buzzing about the significant premium offered and potential windfalls for option holders and biotech investors. Some speculate about other potential buyout targets in the sector, while others discuss the deal's implications for Avidity's pipeline and spun-off cardiology programs.

MannKind Corp. is a biopharmaceutical company, which focuses on the development and commercialization of innovative therapeutic products and devices to address serious unmet medical needs for those living with endocrine and orphan lung diseases. Its products and pipeline include Afrezza, Pediatric Afrezza, V-Go, Tyvaso DPI, MNKD-101, MNKD-201, MNKD-301, and MNKD-501. The company was founded by Alfred E. Mann on February 14, 1991 and is headquartered in Danbury, CT.

Mannkind Corp

Mannkind ($MNKD) is trending amid community discussion around a recent Motley Fool interview with the CEO and its potential implications.  Shareholders are debating the CEO's performance and potential future catalysts like pipeline drugs and partnership opportunities.  The stock's valuation and potential for a merger are also hot topics.

Why Queen Kitty ($QKitty) Is The Meme Token You’ve Been Waiting For  Queen Kitty isn’t just another hype project—this is a real movement with substance and community power!  Why hold $QKitty? 😼 Real dev, real builds: No fake teams, no copy-paste code. Everything you see is made from scratch. 💧 Working Faucet: Free QKitty for the community. Want to know how? Just ask! 🏆 Big Buy Competition Bot: See top buyers live, fight for the throne, and win rewards! 🎮 Multi-token P2E game coming soon: Play and earn across Web, iOS, Android! 🐾 NFT collecting soon: Cutest collection in crypto, bringing perks and more ways to earn.  Queen Kitty means innovation, transparency, and real delivery for holders. Curious? Join the chat and ask anything!  $QKitty: By the community, for the community. To the moon, together! 🚀🐱

Queen Kitty

$QKITTY is trending as the community discusses its trading bot, which some claim generates daily interest. Some users express excitement for upcoming updates, while others share concerns, using the $BROKE tag. The coin is built on Solana, and there are mentions of potential integration with decentralized exchanges.

What is Amp?  Amp is described as the new digital collateral token offering instant, verifiable assurances for any kind of value transfer. Using Amp, networks like Flexa can quickly and irreversibly secure transactions for a wide variety of asset-related use cases.  How does Amp work?  Amp claims to offer a straightforward but versatile interface for verifiable collateralization through a system of collateral partitions and collateral managers. Where collateral partitions can be designated to collateralize any account, application, or even transaction, and carry balances which are directly verifiable on the Ethereum blockchain, collateral managers are smart contracts that can lock, release, and redirect collateral in these partitions as needed in order to support value transfer activities. Amp supports a wide variety of use cases for collateralization, and also introduces the concept of predefined partition strategies, which can enable special capabilities such as collateral models through which tokens can be staked without ever leaving their original address.

AMP Token

AMP Token is trending as the community discusses its potential for real-world utility and adoption, particularly in light of developments around stablecoins and payment infrastructure. Some investors express frustration with the token's price action despite perceived positive news, while others remain optimistic about its long-term prospects, drawing comparisons to traditional payment systems' growth trajectories. Discussions also include speculation about market manipulation and the impact of regulatory clarity on AMP's future.

Amgen, Inc. is a biotechnology company, which engages in the discovery, development, manufacture, and marketing of human therapeutics. The company was founded by William K. Bowes, Jr., Franklin Pitcher Johnson, Jr., George B. Rathmann, and Joseph Rubinfeld on April 8, 1980 and is headquartered in Thousand Oaks, CA.

AMGEN Inc.

AMGN is trending due to ongoing discussions around potential acquisitions and partnerships, particularly concerning companies with innovative drug delivery technologies or promising therapies in areas like inflammation and oncology. The community is analyzing analyst ratings, pipeline developments, and potential strategic moves by AMGN and its competitors. There's also interest in AMGN's positioning within the broader biotech sector amid evolving market dynamics and regulatory landscapes.

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<ul class="summary-bullets"><li>The trial was conducted by &nbsp;Sagimet’s license partner for China, Ascletis Bioscience Co., in 480 patients with moderate to severe acne vulgaris.</li><li>The company said that once daily oral 50 mg Denifanstat achieved highly statistically significant and clinically meaningful improvements across all primary and secondary efficacy endpoints in the study.&nbsp;</li><li>Ascletic said in October that it plans to submit a new drug application to China National Medical Products Administration for Denifanstat for the treatment of moderate-to-severe acne soon. &nbsp;</li></ul>Shares of Sagimet Biosciences Inc. (SGMT) soared 22% by Friday afternoon after its Denifanstat drug yielded positive results in the treatment of acne in a late-stage trial.The trial was conducted by Sagimet’s license partner for China, Ascletis Bioscience Co., in 480 patients with moderate to severe acne vulgaris. It was aimed at evaluating the safety and efficacy of Denifanstat in acne treatment.<h2 class="st-heading-2">Trial Takeaways</h2>Acne vulgaris is a common skin condition caused by clogged hair follicles from oil and dead skin cells, which can result in whiteheads, blackheads, pimples, and in severe cases, painful nodules and cysts.The company <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://ir.sagimet.com/news-releases/news-release-details/denifanstat-achieved-all-endpoints-treatment-moderate-severe">said</a> that once daily oral 50 mg Denifanstat achieved highly statistically significant and clinically meaningful improvements across all primary and secondary efficacy endpoints. Primary endpoints included the percentage change in total lesion count, and the percentage change in inflammatory lesion count, among others.At week 12, treatment success rates with Denifanstat were more than double those of placebo, with marked reductions in both inflammatory and non-inflammatory lesions, it noted.Furthermore, the drug was generally well-tolerated, the company added.<h2 class="st-heading-2">Plans Ahead</h2>Ascletis said in October that it plans to soon submit a new drug application to China National Medical Products Administration for Denifanstat for the treatment of moderate-to-severe acne.Sagimet, meanwhile, is studying the drug in the treatment of metabolic dysfunction associated steatohepatitis, a serious form of liver disease, characterized by fat buildup, inflammation, and liver cell damage.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>On Stocktwits, retail sentiment around<a href="https://stocktwits.com/symbol/SGMT"> SGMT stock</a> jumped from ‘bearish’ to ‘bullish’ territory over the past 24 hours, while message volume increased from ‘normal’ to ‘extremely high’ levels.<figure class="image"><img style="aspect-ratio:622/59;" src="data:image/png;base64,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" width="622" height="59" alt="SGMT's Sentiment Meter and Message Volume as of 2:15 p.m. ET on Oct. 24, 2025 | Source: Stocktwits"><figcaption>SGMT's Sentiment Meter and Message Volume as of 2:15 p.m. ET on Oct. 24, 2025 | Source: Stocktwits</figcaption></figure>A Stocktwits user sounded positive on the stock, citing the size of the Chinese market.<stembedurl>https://stocktwits.com/Mikrus36/message/633613843</stembedurl>SGMT stock has nearly doubled this year.&nbsp;Read also: <a href="https://stocktwits.com/news-articles/markets/equity/gm-reportedly-lays-off-over-200-employees-days-after-raising-2025-earnings-guidance/cLGJFcKR3tb">GM Reportedly Lays Off Over 200 Employees Days After Raising 2025 Earnings Guidance</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

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Sagimet Biosciences Stock Soars After Positive Data For Experimental Drug In Acne Study

The trial was conducted by  Sagimet’s license partner for China, Ascletis Bioscience Co., in 480 patients with moderate to severe acne vulgaris.

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All You Need to Know About Sagimet Biosciences Inc. (SGMT) Rating Upgrade to Strong Buy

Sagimet Biosciences Inc. (SGMT) might move higher on growing optimism about its earnings prospects, which is reflected by its upgrade to a Zacks Rank #1 (Strong Buy).

Ascletis Completes Denifanstat (ASC40) Pre-NDA Consultation with China National Medical Products Administration

Ascletis Completes Denifanstat (ASC40) Pre-NDA Consultation with China National Medical Products Administration Ascletis Completes Denifanstat (ASC40) Pre-NDA Consultation with China National Medical...

Here's Why Sagimet Biosciences Inc. (SGMT) is Poised for a Turnaround After Losing 15.8% in 4 Weeks

The heavy selling pressure might have exhausted for Sagimet Biosciences Inc. (SGMT) as it is technically in oversold territory now. In addition to this technical measure, strong agreement among Wall Street analysts in revising earnings estimates higher indicates that the stock is ripe for a trend reversal.

Sagimet Biosciences Inc. (SGMT) Upgraded to Buy: What Does It Mean for the Stock?

Sagimet Biosciences Inc. (SGMT) has been upgraded to a Zacks Rank #2 (Buy), reflecting growing optimism about the company's earnings prospects. This might drive the stock higher in the near term.

After Plunging 28% in 4 Weeks, Here's Why the Trend Might Reverse for Sagimet Biosciences Inc. (SGMT)

What Makes Sagimet Biosciences Inc. (SGMT) a Strong Momentum Stock: Buy Now?

Wall Street Analysts Predict a 437.05% Upside in Sagimet Biosciences Inc. (SGMT): Here's  What You Should Know

Shares of Sagimet Biosciences soared nearly 40% on Monday, reaching levels not seen since March 2024, as retail sentiment surged following news of an upcoming presentation linked to its lead drug candidate.&nbsp;The clinical-stage biopharma company, which is developing novel therapeutics targeting metabolic and fibrotic diseases, announced that it will present at the 9th Annual MASH-TAG Conference in Park City, Utah, from Jan. 9&nbsp;to 11.The presentation will spotlight the company’s lead drug candidate, denifanstat, an oral, once-daily fatty acid synthase (FASN) inhibitor, which has shown promising results in the Phase 2b FASCINATE-2 study for the treatment of metabolic dysfunction-associated steatohepatitis (MASH).&nbsp;<figure class="image"><img style="aspect-ratio:1318/324;" src="https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/SGMT_sentiment_and_message_volume_Jan_6_fc5e3fb3e0.png" alt="SGMT sentiment and message volume Jan 6.png" width="1318" height="324"><figcaption>SGMT sentiment and message volume Jan 6 as of 11:35 am ET | source: Stocktwits</figcaption></figure>Retail sentiment on Stocktwits turned ‘extremely bullish,’ with Sagimet’s stock trending among the top 20 tickers as of mid-morning.&nbsp;Many investors&nbsp;eagerly await further announcements at the conference, with some buying based on rumors of a significant update.<stembedurl>https://stocktwits.com/GXD_Texas/message/598950606</stembedurl><stembedurl>https://stocktwits.com/valueforme/message/598944787</stembedurl>The study demonstrated a positive anti-fibrotic effect, providing strong support for the drug’s potential in treating liver diseases caused by excessive fat buildup and inflammation.Sagimet’s FASN inhibitors aim to address the dysfunctional metabolic pathways responsible for the overproduction of palmitate, a fatty acid linked to diseases like MASH.&nbsp;Denifanstat’s progress has been noteworthy, with Breakthrough Therapy designation granted by the FDA for treating non-cirrhotic MASH with moderate to advanced liver fibrosis (F2-F3).Oppenheimer’s recent coverage of Sagimet with an ‘outperform’ rating and a $30 price target, which implies more than a 340% upside from current levels, has also contributed to the stock’s upward movement.&nbsp;The brokerage firm highlighted denifanstat’s potential in the MASH market, which is currently dominated by Madrigal Pharmaceuticals’ Resmetirom.&nbsp;Oppenheimer estimates denifanstat could achieve peak revenues of around $1.9 billion by 2040, solidifying its long-term growth prospects.<a href="https://stocktwits.com/symbol/SGMT">Sagimet stock</a> has gained nearly 50% so far this year.For updates and corrections, email newsroom[at]stocktwits[dot]com.

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Sagimet Stock Soars To 10-Month High, Retail’s Fired Up Over Presentation On Lead MASH Drug Candidate

Many investors eagerly await further announcements at the conference, with some buying based on rumors of a significant update.

Ascletis Completes Enrollment of Phase III Trial of ASC40 (Denifanstat) Once-Daily Oral Tablet for Treatment of Acne

Ascletis Completes Enrollment of Phase III Trial of ASC40 (Denifanstat) Once-Daily Oral Tablet for Treatment of Acne Ascletis Completes Enrollment of Phase III Trial of ASC40 (Denifanstat) Once-Daily...

Sagimet Biosciences, Inc. is a clinical-stage biopharmaceutical company, which engages in the development of novel therapeutics for the treatment of infectious diseases. Its lead drug candidate, denifanstat, is an oral, once-daily pill and selective fatty acid synthase (FASN) inhibitor in development for the treatment of nonalcoholic steatohepatitis (NASH). The company was founded by Urs F. Greber, Ari Helenius, and Lucas Pelkmans on December 19, 2006 and is headquartered in San Mateo, CA.

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